Paralytics


Neuromuscular-blocking agents also known as paralytics block neuromuscular transmission at neuromuscular junction, causing loss of motion of skeletal muscles. This is accomplished similarly by acting presynaptically through the inhibition of acetylcholine (ACh) synthesis and by acting postsynaptically at the acetylcholine receptors of the motor nerve end-plate. While a few medications act presynaptically, (for example, botulinum toxin and tetanus poison), those of current clinical significance work postsynaptically. Because the appropriate dose of neuromuscular-blocking medication may paralyze muscles required for breathing (i.e., the diaphragm), mechanical ventilation should to be provided to maintain adequate respiration.


    Related Conference of Paralytics

    November 26-27, 2024

    4th World Congress on Surgery

    Zurich, Switzerland
    November 28-29, 2024

    15th European Conference on Surgery & Cosmetology

    Paris, France
    December 02-03, 2024

    7th Annual Summit on Surgery and Transplantation

    Prague, Czech Republic
    February 24-25, 2025

    11th International Conference on Surgeons

    Madrid, Spain
    May 19-20, 2025

    10th International Conference on Surgery and Anaesthesia

    Zurich, Switzerland

    Paralytics Conference Speakers

      Recommended Sessions

      Related Journals

      Are you interested in