NSAIDs


Nonsteroidal anti-inflammatory drugs are those which reduce pain, fever, prevent blood clots and in high doses, reduce inflammation. Side effects relay upon the particular medication, yet to a great extent incorporate an expanded danger of gastrointestinal ulcers and bleeds, heart attack and kidney disease. The term nonsteroidal distinguishes these medications from steroids, which while having a comparative eicosanoid-depressing, anti-inflammatory activity, have a wide range of different impacts. There are two types of NSAIDs: non-selective and COX-2 selective. Most NSAIDs are non-selective, and inhibit the activity of both COX-1 and COX-2.To begin with utilized as a part of 1960, the term served to remove these drugs from steroids. NSAIDs work by hindering the activity of cyclooxygenase catalysts (COX-1 as well as COX-2).


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