Ahmad Faried currently works as a staff at Department of Neurosurgery and Stem Cell Working Group, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia. He has completed his PhD in Gunma University, Medicine, Japan under supervision of Prof. Hiroyuki Kuwano and Dr. Hiroyuki Kato; received his Postdoctoral grant from JSPS at the same university and continuing his Clinical Fellow in Neurosurgery at The University of Tokyo, Japan under supervision of Prof. Nobuhito Saito. He is a Neurosurgeon with Cell Biology as his back ground. He has a great deal of interest in neuroscience research such as brain microvessel endothelia cells, placental stem cells, neural stem cells, iPSCs, cancer stem cells, neurosurgery, bio-medic engineering especially instrumentation, medical information communication and technology (medical ICT) as well as medical services using cloud computing system.

 Regarding embryonic stem cells (ESCs), in addition to its potential in cell regeneration, is still much debate as well as the rejection of the use of these types of stem cells related the issue of ethics and morals on how to create it (read: sacrifice the embryo). Nuclear transfer is the only way to create ESCs from adult cells (adult stem cells, ASCs). This technique is done by inserting the adult cell nucleus into the egg cell (ovum) whose nuclei had been removed previously. The egg will then reprogram adult cell nuclei into ESCs. This technique is referred to as therapeutic cloning if done in humans, but no one has ever managed to successfully do it. We have recently been amazed by the discovery of RNA interference (RNAi), which unveils new sheets in biomolecular science and its application in surgical sciences, particularly in the modification of the treatment of incurable. Presumably, we must again be amazed at the latest findings in the biomolecular field transformation of skin cells into cells that resemble and function as stem cells, induced pluripotent stem-cells, known as iPS cells. The discovery of iPS  was first introduced by Professor Yamanaka of Kyoto Univ., Japan in 2006. Only by including only four types of genes that can reprogram mature cell (read: adult skin cells) to ESCs. iPS cells are very like the ECS; well as morphology, growth ability, cell surface antigens, gene expression, epigenetic status typical and its telomerase activity. If this technique can be applied to humans, it will be easier to perform compared to the nuclear transfer technique. Furthermore, this technique is inexpensive and does not invite controversy since it does not sacrifice the egg. Long debate about ethical and moral issues about how to create ESCs will fade with the technique of making iPSs. As the reward, this iPS received a Nobel prize in medicine, six years since the invention, which is the fastest Nobel prize in medicine given since it published.

Neil Sheth is an Assistant Professor of Orthopaedic Surgery at University of Pennsylvania. He is also the Pennsylvania Hospital Site Director for the adult reconstruction hip and knee fellowship. He obtained his Under-graduate degree in Biomedical Engineering with a minor in Finance at University of Pennsylvania. He then spent two years on Wall Street as a Financial Analyst at Solomon Smith Barney's Healthcare Investment banking division prior to attending medical school at Albany Medical College. Following medical school, he completed six year Orthopaedic Surgery Residency at Hospital of the University of Pennsylvania. Following residency, he completed an adult hip and knee reconstruction fellowship at Rush University as well as a three-month mini-fellowship at the Endo Klinik in Hamburg, Germany focusing on peri-prosthetic infection. He is currently leading a team to build an orthopedic center of excellence in Moshi, Tanzania.

As the number of primary total hip arthroplasty (THA) procedures performed continues to rise, the burden of revision THA procedures is also expected to increase. With patients undergoing THA at younger ages and living longer, revision patients are presenting with greater bone loss at the time of revision surgery. The proper evaluation and treatment of acetabular bone loss at the time of revision surgery is complex and is further complicated in the face of a chronic pelvic discontinuity. Identifying proper pre-operative patient assessment in conjunction with detailed pre-operative planning is essential for obtaining favorable clinical results. Appropriate radiographs are critical in assessing acetabular bone loss, and specific classification schemes can identify bone loss patterns and guide available treatment options. The presentation reviews the surgical decision making and clinical results of different surgical options for the treatment of acetabular bone loss, and introduces a novel technique for the treatment of a chronic pelvic discontinuity.

Simple algorithms and user-friendly devices provide the  infrastructure for good airway management. It is our professional responsibility to put an end to unnecessary loss of life by ensuring a clear goal of maintaining patient oxygenation. The present variety of video-enhanced airway devices, such as video laryngoscopes and fiberscope have brought further improvements in glottic visualization, but still cannot always guarantee successful passage of endotracheal tube. Combining two of the newer technological innovative devices such as a video laryngoscope and a flexible fiberscope can be complementary and prove critical in a situation where each might fail when deployed alone, even in the most skillful and experienced hands, and reports of such complementary use are still relatively scarce and no specific recommendation is present in the main airway management algorithms. The term multimodal airway approach refers to a combined intubation technique as when the laryn is visualized by video-laryngoscope and the fiberscope is used only as a stylet with movable tip to facilitate endotracheal placement. We present 2 expected difficult intubation cases for 2 male patients aged 26 years and 42 years. We applied conscious sedation by dexmedetomidine, fentanyl, lidocaine and propofol to have consciously sedated patients who were able to tolerate the intubation procedure. Although the videolaryngoscope revealed grade 2 Cormack and Lehane view, it was impossible to pass a bougie into the glottis due to the small mouth opening. Upon utilizing the combined technique of Glidscope-Flexible Fiberscope in one patient and C-MAC – Flexible fiberscope in the other patient, the endotracheal tube was inserted easily in each patient. Awake Multimodal Airway Management (AMAM) can provide safe controlled technique to maximize chances of successful endotracheal intubation and the fiberscope is used only as stylet. We also support and suggest that the American  Society of Anesthesiologists (ASA) can include AMAM in the main ASA airway management algorithm.